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Egidio Vagnozzi (26 February 1906 – 26 December 1980) was an Italian cardinal of the Catholic Church. He served as the second president of the Prefecture for the Economic Affairs of the Holy See from 1968 until his death, and was elevated to the cardinalate in 1967.
In 1930, he also became a staff member of the Secretariat of State in the Roman Curia, and was raised to the rank of Monsignor on 1 May 1932. Before becoming counselor of the Portugal nunciature in 1942, he was a staff member of the Nunciature to the United States in 1932. Vagnozzi was counselor of the French nunciature from 1945 to 1947, and became a Monsignor on 23 December 1945. He was an official of the delegation for the establishment of diplomatic relations with India for a year until becoming chargé d'affaires of the Holy See's mission to the Indian government in New Delhi from June to August 1948.
On 9 March 1949, Vagnozzi was appointed Apostolic Delegate to the Philippines and Titular bishop of Myra. He received his episcopal consecration on the following 22 May from Cardinal Adeodato Giovanni Piazza, OCD, with Archbishops Francesco Borgongini Duca and Roberto Ronca serving as Consecrator. Following the establishment of diplomatic relations between the Holy See and the Philippines government, he was appointed the first Apostolic Nuncio to the Philippines on 9 April 1951. Vagnozzi was named Apostolic Delegate to the United States on 16 December 1958. He attended the Second Vatican Council from 1962 to 1965.
Pope Paul VI created him cardinal deacon of S. Giuseppe in via Trionfale in the Papal consistory of 26 June 1967, and President of the Prefecture for the Economic Affairs of the Holy See on 13 January 1968. After ten years' as a cardinal deacon, Vagnozzi exercised his right to become a cardinal priest, and his deaconry was elevated pro hac vice on 5 March 1973. He was one of the cardinal electors who participated in the Papal conclave of August and October 1978, which selected Popes John Paul I and John Paul II respectively. He was also Chamberlain of the College of Cardinals from 30 June 1979 until his death.
Vagnozzi died in Rome, at age 74. After a Requiem presided by John Paul II in the Lateran Basilica, he was buried in the Campo Verano. His remains were later transferred to his cardinalitial church in March 1983.
Vagnozzi opposed the Marian apparition of Our Lady Mediatrix of All Graces, rejecting its Marian visionary Teresita Castillo, along with six Filipinos local bishops who declared it "Non-Supernatural" in 1956. On 11 December 2015, the Vatican confirmed "the definitive nature of the 11 April 1951 decree by which the phenomena of Lipa were declared to lack supernatural origin." "Prot. N. 226/1949 Presumed Apparitions of the BVM at the Carmelite Convent in Lipa, Philippines," 11 December 2015
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